Polypyrimidine Tract-Binding Protein

A RNA-binding protein that binds to polypyriminidine rich regions in the INTRONS of messenger RNAs. Polypyrimidine tract-binding protein may be involved in regulating the ALTERNATIVE SPLICING of mRNAs since its presence on an intronic RNA region that is upstream of an EXON inhibits the splicing of the exon into the final mRNA product.

Also Known As:

PTB Protein; PTB Splicing Factor; p57 Cytoplasmic RNA-Binding Protein; pPTB; Polypyrimidine Tract Binding Protein; Splicing Factor, PTB; Tract-Binding Protein, Polypyrimidine; p57 Cytoplasmic RNA Binding Protein

Amino Acids, Peptides, and Proteins: 1
- Proteins: 496323
  - Carrier Proteins: 13306
    - RNA-Binding Proteins: 3439
      - RNA Splicing Factors: 1109
        Polypyrimidine Tract-Binding Protein: 118
  - Nucleoproteins: 1892
    - RNA-Binding Proteins: 3439
      - RNA Splicing Factors: 1109
        Polypyrimidine Tract-Binding Protein: 118

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Disease

Drug/Important Bio-Agent (IBA)